• Generic Brand Available - Amikacin
  • API - Amikacin Sulphate
  • Packaging - Vials
  • Strength - 500mg/2mL

What is Amikacin Sulphate, and what it is used for?

Amikacin Sulphate is an aminoglycoside antibiotic used for the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, species of indole-positive, and indole-negative Proteus, Escherichia coli, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species.

Amikacin Dosage

Amikacin injection may be administered once or twice daily and is usually by the intravenous (IV) or intramuscular (IM) route.

Adults and Children: The usual recommended dose of amikacin is 15 mg/kg daily administered in 2 or 3 equally divided doses.
Neonates and Premature Infants: Dosage administered for patients with normal renal function. Start treatment with a loading dose of 10 mg/kg followed by 7.5 mg/kg every 12 hours. The maximum total daily dosage should not be more than 15 mg/kg. Solution infusions via the intravenous route should be given over a 1 to 2-hour period.

Dosage of injection amikacin sulphate is mentioned in terms of amikacin and is calculated on the basis of body weight. Dosage is identical for both routes (IM & IV) of administration.

Amikacin side effects

The most commonly reported side effects due to Amikacin include: skin rash, fever, headache, low blood pressure, numbness and tingling, tremor, nausea, vomiting, increase in white blood cells (eosinophilia), joint pain, anemia, low blood magnesium, dizziness, diarrhea, and hearing loss.

Amikacin Warnings And Precautions
  • Administration of aminoglycosides may impair neuromuscular transmission, and use should be avoided in patients with myasthenia gravis.
  • The amikacin injection uses is restricted in patients with a known history of hypersensitivity to amikacin, any constituents of it or in patients who may have subclinical renal or eighth nerve damage induced by before use of nephrotoxic or ototoxic agents, as the toxicity may possibly be additive.
  • A history of hypersensitivity or severe toxic reactions to aminoglycosides may contraindicate the use of any aminoglycoside due to the known cross-sensitivities of patients to medicines in this class.
  • Patients must be well hydrated during therapy with amikacin. Caution needs to be applied to patients with pre-existing renal insufficiency, pre-existing hearing or vestibular damage, and diminished glomerular filtration.
  • Large doses of amikacin sulfate administered during surgery have been responsible for a condition named transient myasthenic syndrome.
  • Amikacin contains sodium metabisulfite, which may be responsible for causing allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in susceptible individuals.
  • Amikacin medicine must not be used in patients with myasthenia gravis. It should be used with caution in patients with muscular disorders, such as parkinsonism, since these medicines may aggravate muscle weakness due to their potential curare-like effect on neuromuscular junction.
Storage and Handling

Amikacin sulfate injection is a colorless solution. Store this medicinal product at room temperature between 20° to 25°C (68° to 77°F).

Drug Interactions of Abacavir Sulfate
  • If possible, avoid giving amikacin in conjunction with ethacrynic acid, furosemide or other potent diuretics which may themselves cause ototoxicity or increase aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue.
  • There is an enhanced risk of nephrotoxicity and probability of ototoxicity when aminoglycosides including amikacin are used with platinum compounds.
  • The concurrent or sequential administration of other ototoxic, neurotoxic or nephrotoxic agents needs to be avoided either systemically/topically due to the potential for additive effects. Where this is not possible, monitor very carefully.
  • There is an enhanced risk of hypocalcaemia when aminoglycosides including amikacin sulfate are used with bisphosphonates.

Commonly asked questions:

Amikacin is an antibiotic medication used to treat a wide range of bacterial infections.

Amikacin is supplied in the form of injection and dosage of 500mg/2mL dosage strength. 

Amikacin is used by injection into a vein using an IV or into a muscle.

The amikacin 500 mg specifically is a type of drug called aminoglycoside antibiotics. 

It is not specified whether Amikacin enters breast milk; therefore, it is appropriate to be cautious prior to using this medication while breastfeeding.

Amikacin is hazardous to the fetus and its use should be avoided during pregnancy unless there are not safer options.

You can buy Amikacin injection from any authorized wholesaler after getting a prescription from a qualified doctor. It is always better to check the credential of the wholesaler/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product.

Patients can simply fill out the order form or can send mail at Patients can also send WhatsApp messages to +91 8130290915 or can dial the Toll-Free number: 18008891064. We will reply ASAP with the details of the amikacin injection price as well as the procurement procedure.

Note:- The order will be confirmed only after the receipt of the Valid prescription from the Clinician.


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