Atazanavir

  • Innovator Name - Reyataz
  • Generic Brand Available - Atavir
  • API - Atazanavir
  • Packaging - 30 capsules
  • Strength - 100 mg, 150 mg, 200 mg, 300 mg

WHAT IS ATAZANAVIR AND WHAT IT IS USED FOR:

Atazanavir Sulfate (Atavir) is an antiretroviral medication used in the treatment of:

  • Human immunodeficiency virus (HIV); in adult patients who are suffering from severe HIV/AIDS. Medication is used in combination with other antiretroviral agents. 
  • Needlestick injury; Atazanavir may be used in order to prevent injury caused by the penetration by hypodermic needles.
  • Atazanavir belongs to a class named protease inhibitors, which works by stopping the virus from replicating.
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Atazanavir Dosage

Atazanavir 300mg should be taken orally at about the same time each day with food. Capsules should be swallowed whole with water. Atazanavir 300 mg capsules should not be opened, broken, or chewed. The dosage of capsules depends on the body weight and the stage of the disease.

Atazanavir side effects
  • Most common side effects of atazanavir are nausea, jaundice, scleral icterus, rash, headache, abdominal pain, vomiting, insomnia, peripheral neurologic symptoms, dizziness, myalgia, diarrhoea, depression and fever.
  • Gallbladder disorders (which may include gallstones and gallbladder inflammation) have been reported in patients taking REYATAZ (Atazanavir).
  • In some patients with Atazanavir, kidney stones have been reported. If you experience or develop signs or symptoms of kidney stones (pain in your side, blood in your urine, pain when you urinate) tell your healthcare provider promptly.
Warnings and Precautions
  • Use atazanavir 300 mg with more caution in patients with preexisting conduction system disease or when administered with other drugs that may prolong the PR interval.
  • Patients who are carrying hepatitis B or hepatitis C infection are more likely at risk of increased transaminases or hepatic decompensation.
  • Prior to therapy and during treatment, patients should be monitored for hepatic laboratory tests.
  • Atavir should be used with caution in patients with mild to moderate hepatic impairment. Do not use ATAZANAVIR 300mg in patients with severe hepatic impairment.
  • No dose adjustment is required for postpartum patients. Also, patients must be closely and watchfully monitored for adverse events because atazanavir exposures could be higher during the first couple of months after delivery.
  • Atavir should be discontinued if severe rash develops. Cases of Stevens-Johnson syndrome, erythema multiforme, and toxic skin eruptions have been reported in patients receiving Atavir.
  • This antiretroviral is distinguished from other Protease Inhibitors in that it has very less effects on lipid profile and also appears to be less responsible for lipodystrophy.
  • When Atazanavir is boosted with ritonavir, it also reduces the metabolic advantages of atazanavir.
  • Atazanavir is contraindicated in patients with previous hypersensitivity (e.g., erythema multiforme, toxic skin eruptions and Stevens-Johnson syndrome). Also, atazanavir should not be given with rifampin, alfuzosin, lurasidone, irinotecan, pimozide, triazolam, orally administered midazolam, cisapride, St. John’s wort, ergot derivatives, lovastatin, simvastatin, sildenafil, nevirapine or indinavir.
  • The data is not sufficient in order to determine whether there are any effects of race on the pharmacokinetics of atazanavir.
Supplied/Storage and handling

Care should be exercised in the handling of Atazanavir 300 mg. ATAVIR capsules should not be opened or crushed. Store permitted between 20-25°C (68-77°F).

Interactions of Atazanavir

Atazanavir is mainly an inhibitor of CYP2C8, UGT1A1 and CYP3A . Coadministration of REYATAZ and drugs primarily metabolized by CYP3A [eg, calcium channel blockers, immunosuppressants, phosphodiesterase inhibitors and HMG-CoA reductase inhibitors ), UGT1A1 (eg, irinotecan) or CYP2C8 may more likely increase the plasma concentrations of the some other medication which may enhance or prolong its therapeutic as well as adverse effects.

Combination of fluticasone propionate and Atazanavir/ritonavir should not be recommended and also need to be avoided unless some potential advantages to the patient outweighs the risk of systemic corticosteroid adverse effects.

Commonly asked questions:

Yes, Atazanavir is an antiretroviral medication.

Inactive ingredients are crospovidone, lactose monohydrate, and magnesium stearate. The capsule shells are composed of gelatin, FD&C Blue No. 2, titanium dioxide, black iron oxide, red iron oxide, and yellow iron oxide.

This antiretroviral is available as a 300 mg capsule, 200 mg capsule, 150 mg capsule and 50 mg oral powder packet.

The advantage of Atazanavir 300 mg capsules is that it should reduce pill burden, as one 300 mg capsule may replace two 150 mg capsules.

Yes, Atazanavir sulfate was approved for medical use in the United States in 2003. This medication is on the WHO’s (World Health Organization’s) List of Essential Medicines, the safest and most effective medicines needed in a health system.

  • Nausea
  • Dizziness
  • Depression
  • Headache
  • Stomach pain
  • Vomiting
  • Muscle pain
  • Fever
  • Diarrhea

Yes, Atazanavir appears to be safe to use during pregnancy.

Yes, it can be used for prevention after a needlestick injury or other potential exposure.

  • You can buy Atazanavir 300 mg or other strength from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at [email protected]. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Atazanavir Price in India and the procurement procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician

Store the capsules at room temperature, between 68°F to 77°F (20°C to 25°C).

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Atazanavir is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.