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Azacitidine(Tablet)

  • Generic Brand Available - Azatend-O
  • API - Azacitidine
  • Packaging - Tablets
  • Strength - 200 mg and 300 mg

What is Azacitidine, and what it is used for?

Azacitidine is a nucleoside metabolic inhibitor used for continued treatment of adult patients with acute myeloid leukemia (AML) who achieved first complete remission (CR) or complete remission with incomplete blood count recovery (CRi) following intensive induction chemotherapy and can not complete the intensive curative therapy.

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Dosage

The recommended dosage of azacitidine tablet is 300 mg orally once daily with or without food on Days 1’st through 14’th of each 28-day cycle. Continue treatment until the disease is progressive or unacceptable toxicity occurs.

Do not crush, split, or chew the tablets of Azacitidine. Take a dose persistently each day. If a dose is missed, or not taken at the usual scheduled time, take the dose as promptly as possible on the same day, and resume the normal schedule the following day. Avoid taking a couple doses on the very same day. In case a dose is vomited, do not take another dose on the very same day. Resume the general schedule the following day.

Administer an antiemetic 30 minutes before each dose of Azacitidine for the first 2 cycles. Antiemetic prophylaxis may be omitted after 2 cycles in case there has been no vomiting and nausea.

Note: Do not substitute azacitidine tablets for intravenous or subcutaneous azacitidine. The indications and dosing regimen for this medicine differ from that of intravenous or subcutaneous azacitidine.

Side effects

The most commonly reported side effects due to Azacitidine may include: decreased appetite, nausea, vomiting, diarrhea, fatigue/asthenia, febrile neutropenia, constipation, pneumonia, abdominal pain, arthralgia, dizziness, and pain in extremity.

Warnings and Precautions
  • Because of substantial differences in the pharmacokinetic parameters, the standard dose and schedule for azacitidine are different from those for the intravenous or subcutaneous azacitidine products. Do not substitute azacitidine 200 mg or 300 mg pills for intravenous or subcutaneous azacitidine.
  • New or worsening Grade 3/4 thrombocytopenia and neutropenia occurred in those patients who received Azacitidine. Assess complete blood counts and modify the dosage as recommended. Standard supportive care needs to be provided, including hematopoietic growth factors, in case myelosuppression emerges.
  • The safety and effectiveness of azacitidine pills for treatment of myelodysplastic syndromes have not been established. Treatment of patients with myelodysplastic syndromes with azacitidine pills is not recommended.
  • Mechanism of action and findings suggest that, azacitidine 300 mg or 200 mg can cause fetal harm if administered to a pregnant woman. Females of reproductive age should use effective contraception during treatment and for at least 6 months after the final dose.
How Supplied/Storage and Handling

Store the bottles of Azacitidine at temperature 20-25°C (68-77°F); excursions permitted between 15-30°C (59-86°F). Keep bottle well closed. Store and dispense the medication in the original bottle (with 2 desiccant canisters).

Commonly asked questions:

Azacitidine oral is authorized for the treatment of acute myeloid leukemia (AML) in thise who are in remission but cannot complete other treatments for this condition.

This medicinal product is supplied in following dosage strengths, which are as follows:

  • Azacitidine 200 mg tablets
  • Azacitidine 300 mg tablets

 

Azacitidine comes as tablets and to be administered by (mouth) orally. It is typically taken with or without meals once daily. 

It comes in two different forms:

Azacitidine Injection and Tablet

Azacitidine specifically is a type of medicine known as demethylation agents. 

Yes, Azacitadine is a cytotoxic chemotherapy medicine. 

You can buy Azacitidine from any authorized wholesaler after getting a prescription from a qualified doctor. It is always better to check the credential of the wholesaler/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product. 

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial Toll-Free number: 18008891064. We will reply ASAP with the details of the azacitidine tablet price as well as procurement procedure.

Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

Disclaimer

All Trademarks and Brands that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. We are NOT ONLINE store and We do not sell Narcotics and Sedatives. Azacitidine is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Cooperate Sourcing, reseller and Pharmacies.