Azathioprine

  • Innovator Name - Imuran
  • Generic Brand Available - Azapure
  • API - Azathioprine
  • Manufacturer Name - Intas Pharmaceutical Ltd.
  • Packaging - 10 Tablets
  • Strength - 50 mg

WHAT IS AZATHIOPRINE AND WHAT IT IS USED FOR:

Azathioprine is in the purine analogue and antimetabolite family of medication, is indicated for used alone or in combination with other immunosuppressive therapy in order to prevent rejection following organ transplantation and to treat an array of autoimmune diseases, including rheumatoid arthritis, pemphigus, systemic lupus erythematosus, Behçet’s disease, and other forms of vasculitis, autoimmune hepatitis, atopic dermatitis, myasthenia gravis, neuromyelitis optica (Devic’s disease), restrictive lung disease, and others. 

Apart from this, it is also an important therapy and steroid-sparing agent for inflammatory bowel disease (such as Crohn’s disease and ulcerative colitis) and for multiple sclerosis.

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Azathioprine Dosage

Azathioprine 50 mg should be taken orally at about the same time each day, either with or without food. Azathioprine tablets should be swallowed whole with water. The tablets should not be opened, broken, or chewed.

Azathioprine side effects

Most common side effects of Azathioprine include dizziness, diarrhea, fatigue, skin rashes, hair loss, acute pancreatitis, nausea, and vomiting.

Warnings and Precautions
  • Females of childbearing potential must be advised to avoid pregnancy while on Azathioprine.
  • Hair loss is often seen in transplant patients receiving the drug, but rarely occurs under other indications.
  • Azathioprine 50 mg may suppress the bone marrow, patients may develop anaemia and will be more susceptible in order to get infection. Therefore, regular monitoring of the blood count is recommended during the entire treatment.
  • Acute pancreatitis can also occur, especially in patients with Crohn’s disease.
  • People who have previously been treated with an alkylating agent may have an excessive risk of cancers if treated with azathioprine.
  • The use of immunosuppressive medication including azathioprine in organ transplantation has been linked to increased rates of developing skin cancer.
  • Breastfeeding should be avoided whilst taking azathioprine 50 mg tablet.
  • Renal transplant patients are known to have an increased risk of malignancy, predominantly skin cancer, and reticulum cell or lymphomatous tumors.
  • The probability of the risk of post-transplant lymphomas can be increased in those patients who take aggressive treatment with immunosuppressive drugs, including azapure. So immunosuppressive drug therapy needs to be maintained at the lowest effective levels.
  • Patients with TPMT activity (intermediate thiopurine S-Methyl Transferase) more often at an increased risk of myelotoxicity if they are taking conventional doses of azapure (azathioprine).
  • A gastrointestinal hypersensitivity reaction characterized by severe nausea and vomiting has been reported. These symptoms may also be accompanied by diarrhea, rash, fever, malaise, myalgias, elevations in liver enzymes, and occasionally, hypotension.
  • Efficacy, as well as safety of azathioprine in pediatric patients, have not been specified.
Supplied/Storage and handling

Care should be exercised in the handling of AZATHIOPRINE. AZATHIOPRINE tablets should not be opened or crushed. Store permitted between 15°-25°C (59° to 77°F). Stored in a dry place and should be protect from the light.

Commonly asked questions:

Yes, it is approved by the Food and Drug Administration (FDA) for use in kidney transplantation from human donors, and for rheumatoid arthritis.

Azathioprine is a steroid-sparing agent or immunosuppression medicine. Azathioprine keeps the dose of steroids at a minimum level and eventually stops the use of steroids.

Imuran is the brand name under which Azathioprine is sold. Healthcare professionals use it to treat patients who have organ transplants to prevent rejection of the organ and treat an array of autoimmune diseases.

Azathioprine is the active ingredient in the medicine, and lactose, magnesium stearate, potato starch, povidone, and stearic acid are the inactive ingredients in the drug.

Dizziness, diarrhea, fatigue, skin rashes, hair loss, acute pancreatitis, nausea, and vomiting are the most common side effects.

  • You can buy Azathioprine tablets from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Azathioprine is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.