Bevacizumab

  • Innovator Brand Name - Avastin
  • Generic Brand Available - Abevmy
  • API - Bevacizumab
  • Manufacturer Name - Mylan Pharma Pvt Ltd
  • Packaging - Pack of 1 Vial
  • Strength - 400 mg

What is Bevacizumab and what it is used for:

ABEVMY is an angiogenesis inhibitor, indicated for the treatment of:

  • Kidney cancer
  • Brain tumor
  • Ovarian cancer
  • Cervical cancer
  • Non-small cell lung cancer
  • Cancer of colon and rectum
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Bevacizumab Dosage

Abevmy Injection is administered only as an intravenous (IV) infusion. It should be given following the surgical incision has fully healed.
The first infusion is given over 90 minute and the subsequent infusion should be given over 60 minutes in case first infusion is tolerated. All the subsequent infusions should be administered over 30 minutes in case infusion over 60 minutes is tolerated.

Bevacizumab side effects

Most common side effects include High blood pressure, Inflammation of the nose, Headache, Rectal bleeding, Taste change, Nosebleeds, Dry skin, and Protein in the urine.

Warnings And Precautions
  • Discontinue bevacizumab dosage in patients with the fistula formation involving an internal organ.
  • Serious/Fatal gastrointestinal perforation may occur at a higher incidence in patients treated with this drug.
  • Do not use this medicine to patients with the recent history of hemoptysis of ≥1/2 teaspoon of red blood.
  • Avoid bevacizumab uses for 28 days after major surgery and until the surgical wound is fully healed.
  • Nursing or bevacizumab should be discontinued, taking into account the importance of the drug to the mother.
  • Patients should be advised to undergo routine blood pressure monitoring and to contact their health care provider in case of blood pressure is elevated.
  • Infusion should be stopped if a severe infusion reaction developed and appropriate medical therapy should be administered.
Storage and Handling

Care should be exercised in the handling of ABEVMY. ABEVMY injections should not be opened, freezed or shaken. Stores permitted between 2−8°C (36−46°F). Vials should be protected from the light.

Drug interaction of Bevacizumab

No clinically meaningful effect on the pharmacokinetics of irinotecan or its active metabolite SN38, interferon alfa, paclitaxel, or carboplatin was noted when Bevacizumab was used along with these drugs; however, 3 of the 8 recipients receiving Bevacizumab with paclitaxel and carboplatin had lower paclitaxel exposure following 4 cycles of therapy (at Day 63) than those at Day 0, while recipients receiving paclitaxel and carboplatin alone had a greater paclitaxel exposure at Day 63 than at Day 0.

Commonly asked questions:

Yes, FDA approved the drug in 2004 for the treatment of metastatic colorectal cancer.

Bevacizumab is a targeted therapy; it targets cancerous cells and destroys them.

Bevacizumab belongs to the class of medicines named antiangiogenic agents.

The active ingredient in the medicine is Bevacizumab, and the inactive ingredients are α,α-trehalose dihydrate, polysorbate 20, sodium phosphate dibasic, anhydrous, sodium phosphate monobasic, monohydrate, and Water for Injection.

When used for cancer, nose bleeds, headache, rash and high blood pressure are the commonly reported bevacizumab side effects.

The medication must be administered as an infusion. That means you get Avastin bevacizumab through a small needle in your vein or through a port, which is a device that is placed under your skin.

As an anti-angiogenic medication, Abevmy 400 mg Injection works by blocking a protein called vascular endothelial growth factor (VEGF). This helps in stopping the formation of the blood vessels that involve in bringing the oxygen and nutrients to cancerous cells.

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  • Bevacirel 400mg Injection (Reliance Life Science)

You can buy bevacizumab 400 mg injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. The patient can also send a WhatsApp message to +91 8130290915. We will reply ASAP with the details of the bevacizumab cost and procedure.

Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

Disclaimer

All Trademarks and Brands that appear on the website belong to their respective owners and Ikris Pharma Network does not lay any claim on them we only provide Information. Bevacizumab is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, Reseller, and Pharmacies.