• Innovator Brand Name - Angiomax
  • Generic Brand Available - Bivasave
  • API - Bivalirudin
  • Manufacturer Name - Abbott Healthcare Pvt Ltd
  • Packaging - Single-Use Vial
  • Strength - 250mg

What is Bivalirudin and what it is used for:

Bivalirudin specifically is a direct thrombin inhibitor indicated for use as an anticoagulant in patients undergoing:

  • Percutaneous Transluminal Coronary Angioplasty (PTCA)
  • Percutaneous Coronary Intervention (PCI)
  • Also indicated for the treatment of adult patients with unstable angina/ non-ST segment elevation myocardial infarction (UA/NSTEMI) planned for urgent or early intervention.
Bivalirudin Dosage

The recommended dose of Bivalirudin is for intravenous administration only. It is intended for use together with the aspirin (300-325 mg daily) and has been studied only in patients taking concomitant aspirin.

Bivalirudin side effects

The most common adverse reactions include bleeding. Other adverse reactions include thrombocytopenia, fever and headache.

Warnings And Precautions
  • Use of bivalirudin 250 mg injection is contraindicated in patients with active major bleeding and hypersensitivity.
  • Patients should be carefully monitored after primary PCI for signs/symptoms consistent with myocardial ischemia.
  • An increased risk of the thrombus formation, including fatal outcomes, may occur with the use of bivalirudin 250 mg injection in gamma brachytherapy.
  • This medication should be used with caution in patients with disease states associated with an increased risk of bleeding.
  • The infusion dose of bivasave may require to be decreased, and status of anticoagulant should be monitored in patients with renal impairment.
  • Use of bivalirudin injection and aspirin during pregnancy needs to be avoided.
  • Caution must be exercised when this medication is administered to a nursing woman.
Storage and Handling

Care should be exercised in the handling of BIVASAVE. BIVASAVE Injections should not be opened or broken. Store it at 20 to 25°C (68-77°F). Excursions to 15 to 30°C permitted.

Drug interaction of BIVALIRUDIN

In clinical trials in patients undergoing PCI/PTCA, administration of Bivalirudin along with thrombolytics, heparin, warfarin, or GPIs was related to increased risks of major bleeding events in comparison to patients not taking these concomitant drugs. There is no experience with co-administration of Bivalirudin and plasma expanders such as dextran.

Commonly asked questions:

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Bivalirudin specifically belongs to the class of drugs named anticoagulants. 

Thrombocytopenia, fever and headache.

The recommended dose of bivalirudin 250 mg injection is intended for the intravenous bolus injection and continuous infusion. 

As a short, synthetic peptide, Bivalirudinis a potent as well as highly specific inhibitor of the thrombin. It specifically inhibits circulating as well as clot-bound thrombin, while also inhibiting the activation and aggregation of thrombin mediated platelets. Bivalirudin has a rapid onset of action and a short half-life.

The average wholesale bivalirudin price in India is around 9060 INR for a vial of a single injection. 

You can buy Bivalirudin from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at Patient can also send a WhatsApp message to +91 8130290915. We will reply ASAP with the details of Bivalirudin and procedure.

Note:- The order will be confirmed only after the receipt of a Valid prescription of Clinician. 


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Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, Reseller and Pharmacies.