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Cytarabine

  • Generic Brand Name - Cytosar
  • Innovator Brand Name - Cytosine
  • API - Cytarabine
  • Packaging - Single-use Vial
  • Strength - 100mg/500mg/1000mg
  • Manufacturer Name - Pfizer Ltd

What is Cytarabine and what it is used for:

Cytarabine (Cytosine Arabinoside or ara-C), specifically is a chemotherapy medication used for the treatment of acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), chronic myelogenous leukemia (CML), and non-Hodgkin’s lymphoma. 

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Dosage

The recommended cytarabine dose should be administered by infusion into a vein (through a drip) or by injection into a vein or by subcutaneous injection under the direction of your healthcare practitioner.
Your healthcare provider will determine what dose of cytarabine injection to administer and the number of days’ cytarabine treatment you will receive on behalf of your condition.

Treatment Reaction

Most common adverse reactions include back pain, headache, confusion, arachnoiditis, weakness, abnormal gait, convulsions, pyrexia, constipation, fatigue, nausea and vomiting.

Warnings and Precautions
  • Patients taking cytarabine treatment must be monitored closely.
  • The cytarabine uses are contraindicated in patients with hypersensitivity to it.
  • Women of childbearing potential with cytarabine injection are advised to avoid becoming pregnant.
  • Use the medication with caution and possibly at decreased dose in patients with poor liver/kidney function.
  • Periodic evaluations of bone marrow, liver/kidney functions need to be performed in patients with cytarabine 100 mg/500mg/1000mg injection.
  • Patients should stop breast-feeding prior to starting cytarabine therapy because it may be harmful to infants being breast-fed.
  • In patients with the reduced bone marrow, therapy with cytosine injection, must be started under precise medical supervision.
How Supplied/Storage and Handling:

Care should be exercised in the handling of CYTOSAR. CYTOSAR Injections should not be opened or broken. Store at 20°C to 25°C (68°F to 77°F). Protected from the light.

Drug Interaction of Cytarabine
  • Avoid administering Fluorocytosine with Cytarabine as the therapeutic efficacy of 5-Fluorocytosine has been demonstrated to be abolished while on such therapy.
  • Reversible reductions in steady-state plasma digoxin concentrations and renal glycoside excretion were noted in patients with beta-acetyldigoxin and chemo regimens containing cyclophosphamide, vincristine and prednisone either with or without Cytarabine or procarbazine. The steady-state plasma digitoxin concentrations did not appear to change. Thus, monitoring of plasma digoxin levels may be indicated in patients taking similar combination chemo regimens. The utilisation of digitoxin for such patients can be considered as an alternative.
  • An in-vitro interaction study between Cytarabine and gentamicin showed a Cytarabine related antagonism for the susceptibility of K. pneumoniae strains. In patients on Cytarabine and being treated with gentamicin for a K.pneumoniae infection, a lack of a prompt therapeutic response may indicate the need for re-evaluation of antibacterial therapy.

Commonly asked questions:

Cytarabine (cytosar) specifically belongs to the class of drugs named antimetabolite and nucleoside analog. 

  • Biobin 500mg Injection (Cadila Healthcare Ltd)
  • Arasid 500mg Injection (Intas Pharmaceuticals Ltd) 
  • Remcyta 500mg Injection (Alkem Laboratories Ltd) 
  • Cytalon 500Mg Injection (Celon Laboratories Ltd) 

Liver problem, bone marrow suppression, rash, vomiting, diarrhea, bleeding and ulcer formation in the mouth are the common cytarabine side effects

The recommended dose of cytarabine injection should be administered by injection into a vein, under the skin, or into the cerebrospinal fluid. 

Cytosar is the cytarabine brand name, which works in order to block the function of DNA polymerase. 

The average wholesale price for a vial of cytarabine injectable solution is around 1584 INR for a supply of 25 milliliters. 

You can buy Cytarabine from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product. 

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Cytarabine and procedure.

Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician.

Disclaimer

All Trademarks and Brands that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Cytarabine Injection is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, Reseller and Pharmacies.