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Decitabine

  • Generic Brand Name - Mylodec
  • Innovator Brand Name - Dacogen
  • API - Decitabine
  • Packaging - Single-Use Vial
  • Strength - 50mg
  • Manufacturer Name - Celon Labs

What is Decitabine and what it is used for:

Decitabine is a nucleoside metabolic inhibitor indicated in order to treat patients with myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML).

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Decitabine Dosage

The recommended dose should be administered as an injection into the vein under the supervision of a healthcare practitioner. Your healthcare practitioner will determine what dose is appropriate and how often you need to receive it.

Decitabine side effects

Most common adverse reactions include cough, fatigue, neutropenia, hyperglycemia, thrombocytopenia, nausea, anemia, pyrexia, petechiae, constipation, and diarrhea.

Warnings And Precautions
  • Liver chemistries and serum creatinine needs to be obtained before initiation of decitabine 50 mg treatment.
  • Platelet counts and complete blood counts should be performed as required in order to monitor response as well as toxicity, but at a minimum, before each cycle.
  • Women of the childbearing potential should be apprised to avoid becoming pregnant while taking treatment with decitabine 50 mg.
  • Male patients should be apprised not to father a child during treatment with this medication, and for 2-months after finishing the treatment.
  • Following administration of the recommended decitabine dosage for the 1st cycle, treatment for the subsequent cycles need to be adjusted.
  • Myelosuppression and worsening neutropenia may occur a bit frequently in the 1st or 2nd treatment cycles, and may not necessarily show progression of the underlying MDS.
  • Mylodec always should be used with the extra caution in patients with renal and hepatic impairment.
Storage and Handling

Care should be exercised in the handling of MYLODEC. MYLODEC injections should not be opened or broken. Store vials at 25°C (77°F); excursions permitted to 15 to 30°C (59­-86°F).

Drug interaction of Decitabine

Drug interaction findings along with decitabine have not been conducted. In vitro findings in human liver microsomes suggest that decitabine is unlikely to inhibit or induce the cytochrome P450 enzymes. In vitro metabolism findings have suggested that decitabine is not a substrate for human liver cytochrome P450 enzymes. As plasma protein binding of decitabine is negligible (<1 percent), interactions due to displacement of more highly protein bound drugs from plasma proteins are not expected.

Commonly asked questions:

The FDA approved the drug Decitabine in 2006.

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  • Decitex 50mg Injection (Sun Pharmaceutical Industries Ltd)
  • Natdecita 50mg Injection (Natco Pharma Ltd)
  • Decitas 50mg Injection (Intas Pharmaceuticals Ltd)
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As a hypomethylating agent, decitabine works in order to switch off a protein named DNA methyltransferase. This switches on the genes that block the cancerous cells growing as well as dividing.

Decitabine belongs to a class of drugs known as DNA demethylating agents.

 

The active ingredient in the medicine is Decitabine, and the inactive ingredients are monobasic potassium phosphate (potassium dihydrogen phosphate) and sodium hydroxide.

Nausea, fever, vomiting, diarrhea, headache, and lung infection.

The recommended dose of decitabine should be administered as an infusion into the vein (intravenous or IV).

You can buy Decitabine from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of decitabine injection and procedure.

Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician.

Store the medicine at a temperature of 25°C (77°F).

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. MYLODEC Injection is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, Reseller and Pharmacies.