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Efavirenz Emtricitabine Tenofovir

  • Brand Name - Teevir
  • Innovator Brand Name - Atripla
  • API - Efavirenz, Emtricitabine, and Tenofovir Disoproxil Fumarate.
  • Packaging - 30 Tablets
  • Strength - Efavirenz 600mg + Emtricitabine 200mg + Tenofovir 300mg
  • Manufacturer Name - Mylan Pharma Pvt Ltd.

WHAT IS EFAVIRENZ EMTRICITABINE AND TENOFOVIR AND WHAT IT IS USED FOR:

Efavirenz is a non-nucleoside reverse transcriptase inhibitor, Emtricitabine is a nucleoside analog reverse transcriptase inhibitor and Tenofovir disoproxil is also a nucleotide analog reverse transcriptase inhibitor indicated for the treatment of HIV/AIDS.

Teevir is a combination (fixed dose) of efavirenz, emtricitabine, and tenofovir disoproxil. It can be used by itself or together with other antiretroviral medications. 

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Efavirenz Emtricitabine and Tenofovir Disoproxil Fumarate dosage

Teevir should be taken orally at about the same time each day, at or before bedtime on an empty stomach in order to reduce side effects. Teevir tablets should be swallowed whole with water. The tablets should not be opened, broken, or chewed.

Efavirenz Emtricitabine and Tenofovir side effects
  • Most common side effects of Teevir (efavirenz/emtricitabine/tenofovir) include headache, trouble sleeping, sleepiness, and unsteadiness.
  • Some serious adverse reactions include high blood lactate levels, psychiatric symptoms, and enlargement of the liver.
  • Some other additional side effects are allergic reaction (including swelling of the face, lips, tongue, or throat), inflammation of the pancreas, shortness of breath, pain, stomach pain, weakness and indigestion.
Warnings and Precautions
  • Efavirenz/emtricitabine/tenofovir should not be used in children.
  • If this medication used during the first trimester of pregnancy harm to the baby may occur.
  • People who have shown strong hypersensitivity to efavirenz, should not take efavirenz/emtricitabine and tenofovir.
  • Breastfeeding is contraindicated while on this medication.
  • Some mentioned drugs are contraindicated include: ergot derivative drugs, voriconazole, benzodiazepines midazolam and triazolam, calcium channel blocker bepridil, cisapride, pimozide and Hypericum perforatum.
  • People with liver or kidney problems who are taking medications associated with liver toxicity should be monitored liver function and should receive one tablet by mouth once a day.
  • Need to monitor the liver function test prior and also while on the treatment in patients who carried underlying hepatic disease, including hepatitis B or C coinfection, marked transaminase elevations.
  • Discontinue efavirenz emtricitabine tenofovir disoproxil fumarate in circumstances of development of severe rash.
  • Tenofovir disoproxil fumarate increases didanosine concentrations. So use with caution and patient should be monitored for evidence of didanosine toxicity (pancreatitis, neuropathy) when coadministered.
  • Teevir is not recommended for patients with moderate or severe hepatic impairment.
  • In adults and also in pediatric patients with efavirenz, cases of convulsions have been observed. Generally, this observation is with known medical history of seizures. Caution should be taken in such patients who are with a history of seizures.
  • Patients who are receiving concomitant anticonvulsant medications primarily metabolized by the liver, such as phenytoin and phenobarbital, may require periodic monitoring of plasma levels.
Supplied/Storage and handling

Care should be exercised in the handling of TEEVIR. Teevir capsules should not be opened or crushed. Keep this medication in the tightly closed container. Store permitted between 15-30°C (59-86°F).

Interactions of Efavirenz Emtricitabine and Tenofovir
  • Drug InteractionLopinavir/ritonavir and Darunavir with ritonavir have been shown to increase the concentrations of Tenofovir.
  • Tenofovir DF is a substrate of P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) transporters. When tenofovir DF is coadministered with an inhibitor of these transporters, an enhancement in the absorption may occur.
  • People with strong hypersensitivity to the efavirenz, should be avoided the consumption of efavirenz/emtricitabine/tenofovir.

Drugs which are contraindicated areas follows:

  • Voriconazole and Cisapride
  • Ergot derivative drugs
  • Benzodiazepines midazolam and triazolam
  • Calcium channel blocker bepridil
  • Pimozide and St. John’s wort (Hypericum perforatum)
  • Breastfeeding is also contraindicated

Commonly asked questions:

In the year 2006, in the US Efavirenz/emtricitabine/tenofovir was approved as a once-daily tablet in order to treat HIV.

The active ingredients in Teevir are efavirenz, emtricitabine, and tenofovir disoproxil fumarate, and the inactive ingredients are croscarmellose sodium, hydroxypropyl cellulose, microcrystalline cellulose, magnesium stearate, sodium lauryl sulfate. The film coating contains black iron oxide, polyethylene glycol, polyvinyl alcohol, red iron oxide, talc, and titanium dioxide.

Teevir does not cure HIV or AIDS, and after taking this medicine, one may continue to experience illnesses associated with HIV-1 infection, including opportunistic infections.

Yes.

The main advantage of this drug is that it could be taken once daily and reduce the overall stress in an antiretroviral regimen.

  • You can buy Teevir or efavirenz emtricitabine tenofovir disoproxil fumarate from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician

Do not open or crush the medicine.
Keep the medicine Teevir in a tightly closed container.
Store the medicine between 15-30°C (59-86°F).

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Efavirenz Emtricitabine and Tenofovir is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.