Everolimus

  • Brand Name - Evermil
  • Innovator Brand Name - Afinitor
  • API - Everolimus
  • Packaging - 10 tablet
  • Strength - 10 mg
  • Manufacturer Name - Glenmark

WHAT IS EVEROLIMUS AND WHAT IT IS USED FOR:

Everolimus is a kinase inhibitor drug  indicated for the treatment of: 

  • Postmenopausal women suffering from breast cancer with hormone receptor-positive and HER2- negative in combination with exemestane.
  • Patients suffering from advanced neuroendocrine tumors originated from the pancreas (PNET).
  • Patients suffering from advanced renal cell carcinoma (RCC)  after the failure of treatment with sorafenib or sunitinib.
  • Adults suffering from tuberous sclerosis complex (TSC) and renal angiomyolipoma which is not requiring immediate surgery.
  • Patient with above 3 years of suffering from subependymal giant cell astrocytoma (SEGA) with tuberous sclerosis complex (TSC)
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Everolimus Dosage

Everolimus should be taken orally at about the same time each day, either with or without food. Everolimus tablets should be swallowed whole with water. The tablets should not be emptied, smashed, or eaten.

There are several factors on which the everolimus dosage depends.

Everolimus side effects

Breast cancer, PNET, RCC: some common everolimus side effects of using this drug in mentioned cases are abdominal pain, cough, infections, stomatitis, rash, edema, fever, nausea, diarrhea, fatigue, decreased appetite, and headache.

SEGA: adverse reactions include pyrexia, upper respiratory tract infection, otitis media, and sinusitis.

Warnings and Precautions
  • Non-infectious pneumonitis: regularly monitor for any symptoms. Discontinue or reduce the dosage of everolimus 0.5mg  when symptoms appear. Few cases may cause fatalities.
  • Oral ulceration: oral mucositis, mouth ulcer, and stomatitis are very common when using this drug for treatment.
  • Infections: the patient is at high risk of infection. Patients taking everolimus 0.25mg should reduce the dose if any infectious symptoms appear.
  • Renal failure: in a few cases renal failure may lead to fatal outcomes.
  • Vaccination: Patients taking everolimus drugs should avoid taking live vaccinations or stay away from a patient having the vaccination.
  • Embryo-fetal damage: if this drug is administered to pregnant women that may cause potential harm to the embryo.
Supplied/Storage and handling

Care should be exercised in the handling of Everolimus. Everolimus tablets should not be opened or crushed. Short term store permitted at 30°C for 3 or 7 days and for long term at -20°C for 0-90 days.

Commonly asked questions:

Everolimus belongs to an mTOR kinase inhibitor class and is an antineoplastic chemotherapy drug.

This medicine is an inhibitor of mTOR and is an antineoplastic agent (chemotherapy drug). It is a targeted therapy; Everolimus is a kinase inhibitor that inhibits mTOR, an enzyme responsible for cell growth.

A pharmaceutical drug, a protein kinase inhibitor, is an enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases are those enzymes that add a phosphate (PO4) group to a protein and modulate its function.

Some self-care tips are listed below:

  • Drink at least 2-3 liters of water for every 24-hour cycle.
  • Avoid going to crowded places as the chances of infection is high.
  • Rinse your hands more frequently with foam and water.
  • Use a razor and toothbrush carefully to minimize bleeding.
  • If the patient feels nausea, take anti-nausea pills as prescribed by the doctor.
  • Avoid sun exposure as it can cause sunstroke.
  • Eat nutritious food.
  • Get plenty of sleep for about 7 to 8 hours.
  • Completely avoid alcoholic beverages.

The tablets of Everolimus strength are available only in 10 mg.

Some common side effects include:

  • Rash
  • Infections
  • Diarrheas
  • Cough
  • Weakness
  • Cough
  • You can buy Everolimus from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at [email protected]. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Everolimus is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.