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Fulvestrant

  • Generic Brand Name - Fulvestrant
  • Innovator Brand Name - Faslodex
  • API - Fulvestrant
  • Packaging - 2×5ml
  • Strength - 250mg/5ml
  • Manufacturer Name - Samarth life science

What is Fulvestrant and what it is used for:

Fulvestrant is an estrogen receptor antagonist used for the treatment of:

  • HR +Ve metastatic breast cancer in the postmenopausal women with disease progression.
  • HR +Ve, HER2 -Ve advanced breast cancer along with palbociclib in women with disease progression after the therapy of endocrine.
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Dosage

The recommended fulvestrant dose is 500 mg, should be administered intramuscularly into the buttocks slowly (1 to 2 minutes per injection) as two 5 mL injections, one in each buttock, on the days 1’st, 15’th, 29’th and once monthly thereafter.

side effects

Most common adverse reactions include bone pain, hot flash, musculoskeletal pain, nausea, arthralgia, injection site pain, headache, pain in extremity, cough, vomiting, constipation, back pain, fatigue, anorexia, asthenia, and dyspnea.

Warnings And Precautions
  • The fulvestrant uses are normally contraindicated in patients with the known hypersensitivity to it or any of its existing components.
  • The faslodex 250 injection should be used with caution in patients with thrombocytopenia, bleeding diathesis, or anticoagulant use.
  • Caution should be imposed while administering faslodex at the dorsogluteal injection site due to the proximity of the underlying sciatic nerve.
  • A fulvestrant 250 mg dose is recommended in patients with the moderate hepatic impairment.
  • Women must be apprised of the potential hazard to the fetus and to avoid becoming pregnant while on Faslodex.
  • Breastfeeding is restricted while on the therapy with fulvestrant 250 mg.
How Supplied/Storage and Handling:

Care should be exercised in the handling of FASLODEX. FASLODEX Injections should not be opened or broken. Refrigerate, 2°C to 8°C (36°F to 46°F). In order to protect from the light, store in the original carton until the time of use.

Drug interaction of FULVESTRANT

There are no known drug-drug interactions. Although fulvestrant is metabolized by CYP 3A4 in vitro, drug interactions studies with ketoconazole or rifampin did not alter fulvestrant pharmacokinetics. Dose adjustment is not required in patients co-prescribed CYP3A4 inhibitors or inducers.

Commonly asked questions:

Fulvestrant specifically belongs to the class of drugs named estrogen receptor antagonists. 

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  • Fuvestrol 250mg Injection (Cadila Pharmaceuticals Ltd) 
  • Fulviglen 250mg Injection (Glenmark Pharmaceuticals Ltd) 
  • Fasnorm 250mg Injection (Biocon Ltd) 
  • Celvestrant 250mg Injection (Celon Laboratories Ltd)

Hypersensitivity reactions, hot flushes, urinary tract infections, loss of appetite, blood clots in veins, headache, vomiting, diarrhea, elevated bilirubin, back pain and rashes are the common fulvestrant side effects

The recommended dose of fulvestrant injection should be administered by injection into a muscle.

As a SERD (Selective Estrogen Receptor Degrader), fulvestrant works in order to bind to the estrogen receptor and destabilize it, causing the cell’s protein degradation actions to kill it.

The average wholesale fulvestrant injection price in India for 50 mg/mL is around 146,448 INR for a supply of 10 milliliters.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of inj fulvestrant and procedure.

Note:- The order will be confirmed only after the receipt of a Valid prescription of Clinician.

Disclaimer

All Trademarks and Brands that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Fulvestrant Injection is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, Reseller and Pharmacies.