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Idarubicin

  • Generic Brand Name - Zavedos
  • Innovator Brand Name - Zavedos & Idamycin
  • API - Idarubicin Hydrochloride
  • Packaging - Single-Use Vial
  • Strength - 5mg, 10mg
  • Manufacturer Name - Pfizer

What is Idarubicin and what it is used for:

ZAVEDOS is an anthracycline antileukemic drug indicated for the treatment of: 

  • Acute non-lymphocytic leukemia (ANLL) as a first line in adult patients. 
  • Acute lymphocytic leukemia (ALL) as a second line in adults and children. 
  • Chronic myelogenous leukemia in blast crisis.
  • Advanced breast cancer.
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Idarubicin dosage

Zavedos intravenous injection in combination with other drugs daily should be given by continuous infusion. The dosage of zavedos is usually calculated on the basis of total body surface area.

Idarubicin side effects

Most common adverse reactions include Nausea, Vomiting, Diarrhea, Sores in the mouth and throat, Stomach pain, Headache, Joint pain, Hair loss, Rash, and Redness/blisters on the palms and soles.

Warnings And Precautions of Idarubicin
  • The idarubicin 5 mg must be administered only under the supervision of a healthcare practitioner experienced in the use of cytotoxic chemotherapy.
  • Avoid using this drug in patients with pre-existing bone marrow depression induced by the radiotherapy unless the benefit warrants the risk.
  • The idarubicin hydrochloride is contraindicated in pregnant women or women wishing to become pregnant.
  • Patients should be assessed for cardiac function before undergoing treatment with zavedos 5 mg and must be monitored throughout therapy in order to minimize the risk of incurring severe cardiac impairment.
  • Men as well as women should seek advice on fertility preservation prior to starting treatment with idamycin.
  • Women of childbearing potential should be instructed to not become pregnant while on treatment.
Storage and handling

Care should be exercised in the handling of ZAVEDOS. ZAVEDOS injections should not be opened or crushed. Stores permitted between 15° to 30°C (59° to 86°F), and protect from light.

Drug interaction of IDARUBICIN
  • Idarubicin basically is a potent myelosuppressant and combination chemo regimens that comprised other agents with identical action (e.g., other anthracenediones, anthracyclines) may lead to additive toxicity, mainly with regard to the bone marrow or hematologic and gastrointestinal effects.
  • The administration of idarubicin in combination chemo with certain other potentially cardiotoxic medicines (e.g., cyclophosphamide, paclitaxel), as well as the concomitant administration of other cardioactive compounds (e.g., calcium channel blockers such as diltiazem, amlodipine, or verapamil), needs monitoring of cardiac function throughout the therapy.
  • Changes in the renal/hepatic function induced by concomitant therapies may affect idarubicin metabolism, pharmacokinetics, and therapeutic efficacy and toxicity.
  • An additive myelosuppressant effect may be established when radiotherapy is given concomitantly or within two to three weeks prior to therapy with idarubicin.

Commonly asked questions:

The active ingredient in the medicine is Idarubicin hydrochloride, and the inactive ingredient is Lactose NF.

The medicine Idarubicin is a sterile, semi-synthetic antineoplastic (cytotoxic) anthracycline drug.

The idarubicin hydrochloride belongs to the class of drugs named antitumor antibiotics.

Nausea, diarrhea, stomach cramps, and vomiting are commonly reported idarubicin side effects

The idarubicin 5 mg must be administered only by injection slowly into a vein. Avoid giving by injection into a muscle or under the skin.

Falls under anthracyclines class of medicines, zavedos specifically works by slowing or resisting the growth of cancer cells in the body.

You can buy idarubicin hydrochloride from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product. 

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.

Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician.

Store the medicine at temperature 15° to 30°C (59° to 86°F). Protect the medicine from light.

Disclaimer

All Trademark and Brand that appear on website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. We are not an ONLINE store and we do not sell Narcotics and Sedatives. Idarubicin is a pharmaceutical drug that legally requires a medical prescription to be dispensed. Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Cooperate Sourcing, reseller, and Pharmacies.