Melphalan

  • Brand Name - Alkacel
  • Innovator Brand Name - Alkeran
  • API - Melphalan Hydrochloride
  • Packaging - Single Use Vial
  • Strength - 50 mg per vial
  • Manufacturer Name - Celon Labs

WHAT IS MELPHALAN AND WHAT IT IS USED FOR:

Alkacel is an alkylating drug indicated for the treatment of:

  • Multiple Myeloma (A type of blood cancer). 
  • Ovarian Cancer (A type of female organ cancer that produces eggs).
  • AL amyloidosis (Also known as primary amyloidosis). 
  • And malignant melanoma (A type of cancer that develops from the pigment-producing cells known as melanocytes).
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Melphalan Dosage

Melphalan 50 mg should be given as an injection or infusion into vein under the supervision of an experienced healthcare provider.

Melphalan side effects

Most common Melphalan’s side effects include white blood cell count decreased, diarrhea, platelet count decreased, vomiting, anemia, nausea, fatigue and hypokalemia.

Warnings and Precautions
  • Patients with a history of skin rash with other alkylating agents (e.g., chlorambucil) may have increased risk of rash with melphalan.
  • Breastfeeding is not recommended while on dose of Melphalan.
  • Generally melphalan should not be used concurrently with radiation, however melphalan has been used with radiation for the treatment of multiple myeloma.
  • Administer with caution in patients with bone marrow suppression, and/or in patients whose bone marrow reserve may be compromised by recent chemotherapy or radiation.
Supplied/Storage and handling

Care should be exercised in the handling of Melphalan Injection. Melphalan should retain in the original carton until use. Store permitted between 15-30°C (59-86°F).

Drug interaction of Melphalan
  • Establishment of severe renal failure has been noted in patients treated with a single dose of IV melphalan followed by standard oral doses of cyclosporine.
  • Cisplatin may be responsible for affecting melphalan kinetics by inducing renal dysfunction and subsequently altering melphalan clearance. IV melphalan may also be responsible for reducing the threshold for BCNU lung toxicity.
  • When nalidixic acid and IV melphalan are administered simultaneously, the incidence of severe hemorrhagic necrotic enterocolitis has been noted to increase in pediatric patients.

Commonly asked questions:

It is an alkylating agent of the bis chloroethyl amine type and a chemotherapy drug used to treat various cancers.

The active ingredient in the medicine is Melphalan hydrochloride, and the inactive ingredients are Betadex Sulfobutyl Ether Sodium.

It is not specified if Alkacel is safe and effective in children.

Yes, Melphalan tablets, manufactured by Celon labs, are available.

  • Melphalan price is low if you go with generic brand, you can buy Melphalan from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at [email protected]. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician

Store the medicine in the original carton only before use.
Store it at room temperature from 15-30°C (59-86°F).

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Melphalan Injection IP 50 mg is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.