Mitomycin injection must be given I.V intravenously only, care is recommended in order to avoid the extravasation of the compound. Each vial contains 0.2 mg of mitomycin and 0.4mg of mannitol in 1:2 ratio. For its use it is mixed with 1 ml of sterile water this is shaken to dissolve and then injected.
Mitomycin
- Brand Name - Mitomycin 40
- Innovator Brand Name - Mitosol
- API - Mitomycin
- Packaging - Single-Use Vial
- Strength - 40mg
- Manufacturer Name - Zydus
WHAT IS MITOMYCIN AND WHAT IT IS USED FOR:
Mitomycin is an antimetabolite injection used in the treatment of glaucoma filtration surgery, pancreatic cancer, stomach cancer. It is also used in the treatment of several disorders that are related to the growth and multiplication of cells.
Mitomycin Injection Dosage
Mitomycin side effects
The most common side effects of mitomycin include fever, anorexia, nausea, vomiting. Other side effects are blurring of vision, headache, confusion, drowsiness, fatigue, edema, syncope, thrombophlebitis, hematemesis, pain, and diarrhea.
Warnings and Precautions
- High dose of mitomycin 40 mg or mitomycin 10 mg may cause cell death as it is toxic to cells.
- Mitomycin is not recommended to replace appropriate surgery or radiotherapy.
- Mitomycin should not be used in patients who have an idiosyncratic reaction or demonstrated hypersensitivity.
- Patients taking mitomycin must be observed for the evidence of renal toxicity.
- Mitomycin should be avoided in patients who carried a serum creatinine.
- Mitomycin can cause fetal harm when administered to a pregnant woman. Uses of Mitomycin injection in pregnancy or a patient becomes pregnant while on this drug can cause harm to the unborn baby.
- Severe bronchospasm and Acute shortness of breath have been observed following the administration of vinca alkaloids in patients who had previously or simultaneously received mitomycin.
- Deep care, as well as attention, should be paid in order to fluid balance and overhydration need to be avoided.
- Instruct patients to discuss with their physician if they are pregnant or if they might become pregnant.
- In order to safety and effectiveness, there are no differences observed between elderly and younger patients.
Supplied/Storage and handling
Mitomycin C should be stored at controlled room temperature 15°-30° C (59°-86°F) and protected from light. The standard temperature to be stored is at 25 degree Celsius.
Drug interaction of Mitomycin
- The myelotoxic interactions with other bone marrow-toxic treatment modalities (mainly other cytotoxic medicinal products, radiation) are possible.
- Combination with bleomycin or vinca alkaloids may reinforce pulmonary toxicity.
- An increased risk of haemolytic uremic syndrome has been noted in patients with concomitant use of mitomycin and fluorouracil or tamoxifen.
- No injections with live vaccines should be carried out in connection with the mitomycin treatment.
- The cardiotoxicity of Adriamycin (doxorubicin) may be reinforced by mitomycin.
Commonly asked questions:
Mitomycin is an antibiotic isolated from the broth of Streptomyces verticillus Yingtanensis. The medicine is a sterile lyophilized mixture of Mitomycin and Mannitol.
Yes, it was approved by the FDA in 1974, initially approved for the U.S only.
Mitomycin 40 mg is used to treat symptoms of pancreatic and stomach cancer and is under clinical research for its potential to treat
- Gastrointestinal strictures
- Wound healing from glaucoma surgery
- Corneal excimer laser surgery
- And endoscopic dacryocystorhinostomy.
The active ingredient of the medicine is Mitomycin, and the inactive ingredient is Mannitol.
- You can buy Mitomycin from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
- The buyer should check the existing law in their home country before importing the product.
Patients can simply fill the order form or can send mail at [email protected]. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician
Disclaimer
All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Mitomycin is a pharmaceutical drug that legally requires a medical prescription to be dispensed.
Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.
