Nintedanib

  • Brand Name - Cyendiv
  • Innovator Brand Name - Ofev & Vargatef
  • API - Nintedanib
  • Packaging - 60 Capsules
  • Strength - 100 mg, 150 mg
  • Manufacturer Name - Boehringer Ingelheim

WHAT IS NINTEDANIB AND WHAT IT IS USED FOR:

Nintedanib is a pharmaceutical drug that inhibits tyrosine kinase and indicated for the treatment of:

  • Idiopathic Pulmonary Fibrosis: Nintedanib used to treat the IPF (Idiopathic Pulmonary Fibrosis). It works in order to block such substances that cause IPF.
  • Non-Small Cell Lung Cancer (NSCLC): In combination with docetaxel for the patient with locally advanced, metastatic or locally recurring non-small cell lung cancer. Nintedanib can be used as a second-line treatment with a combination of Docetaxel.
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Nintedanib Dosage

Nintedanib 150 mg (cyendiv 150 mg) should be taken orally at about the constant time each day, intended to have a systematic effect, reaching/spreading different parts of the body via the bloodstream.

This medication should be taken with food for better absorption, Rather than chewing or crushing, gulped it whole with fluid otherwise it may leave a bitter taste on your tongue.

Nintedanib side effects

The most common adverse reactions of Nintedanib capsules may include nausea, decreased appetite, vomiting, abdominal pain, diarrhea, weight loss, headache, low thyroid, and bleeding.

Apart from this some serious adverse reactions may also occur including Liver Toxicity and Elevated Transaminase Levels.

Warnings and Precautions
  • Females who`re looking to conceive a baby, shouldn’t take this medication else it may directly affect the fertility.
  • It should be avoided by females during the time period of breastfeeding.
  • Before starting the course of Nintedanib, talk to your medical expert about your medical as well as family history.
  • If you`re allergic to this medication, do not take it without the advice of your pharmacist.
  • This medication should not be used in a patient with Hepatic insufficiency (Hepatic Impairment).
Supplied/Storage and handling

Care should be implemented in the proper handling of Ofev Medication (Nintedanib). Nintedanib tablets should not be opened or crushed unnecessarily.

The store permitted for this medication should be between 15-30 C (59-86 F).

Drug interaction of Nintedanib
  • Nintedanib is a substrate of P-gp and, to a minor extent, CYP3A4. The Concomitant administration of P-gp and CYP3A4 inhibitors (e.g. erythromycin) with Nintedanib may increase exposure to nintedanib. In such cases, monitor patients closely for tolerability of Nintedanib.
  • Concomitant administration of P-gp and CYP3A4 inducers (e.g., phenytoin, carbamazepine, and St. John’s wort) with Nintedanib should be avoided as these drugs may reduce the exposure to nintedanib.
  • Nintedanib is a VEGFR inhibitor, and may be responsible for increasing the risk of bleeding. Assess patients on full anticoagulation therapy precisely for bleeding and adjust anticoagulation treatment as necessary.

Commonly asked questions:

NSCLC (Non-Small Cell Lung Cancer) is a kind of epithelial Cell Cancer. Which accounts for approximately 85% of entire existing lung cancer. People who smoked may more likely to get this sort of cancer.

It is classified into three types: Adenocarcinoma, Large Cell Carcinoma and Squamous Carcinoma.

Nintedanib belongs to the tyrosine kinase inhibitor drug.

Yes.

The medicine’s active ingredient is Nintedanib, and the inactive ingredients are triglycerides, hard fat, lecithin. Capsule Shell: gelatin, glycerol, titanium dioxide, red ferric oxide, yellow ferric oxide, black ink.

People who should avoid the administration of Nintedanib are:
Heart-related problems
Liver-related problems
History of blood clots
Had recent surgery stomach (abdominal) area
Pregnant or planning to become males and females
Breastfeeding mothers

  • You can buy Nintedanib 150 mg or Nintedanib 100 mg from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Nintedanib is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.