The medicine Normosang is used to treat patients with acute attacks of hepatic porphyria (acute intermittent porphyria, porphyria variegata, hereditary coproporphyria). Normosang is supplied 250 mg/10 ml to administer in a large antebrachial or central vein for 30 minutes.
Indication and Dosage
Normosang is used in treating patients with acute attacks of hepatic porphyria:
The recommended dose of Normosang injection is 3 mg/kg once daily for four days, diluted in 100 ml of 0.9% sodium chloride in a glass bottle and infused intravenously over at least 30 minutes into a large antebrachial or central vein using an inline filter. The dose should not exceed 250 mg (1 ampoule) per day.
Method of Administration
The infusions should be administered in a large antebrachial or central vein over at least 30 minutes. After the infusion, one should rinse the vein with 100 ml of 0.9 % NaCl. It is recommended to flush the vein initially with 3 to 4 bolus injections of 10 ml 0.9 % NaCl after which the remaining volume of saline can be infused for 10 – 15 minutes.
Common Side effects
One should consult healthcare professionals before administering Normosang (Human Hemin) due to the medicine’s adverse effects. The most common side effects of Normosang are
Note from Ikris Pharma Network
Acute hepatic porphyria (APH) is rare, and general awareness of the condition is low. When acute symptoms strike in a sudden attack, they can be confusing and frightening. Some people spend years discovering what might be wrong with them and what might help. If one suspects they might have APH, healthcare professionals will conduct a thorough physical examination and ask about your medical history, including any symptoms you have been experiencing. In addition, laboratory testing of your urine, blood, and feces and genetic testing will be conducted to make a definite diagnosis. Once the person knows, they will be better positioned to prevent and manage attacks.