Oxaliplatin

  • Brand Name - oxa
  • Innovator Brand Name - Eloxatin
  • API - Oxaliplatin
  • Packaging - Single-use vial
  • Strength - 50 mg, 100 mg
  • Manufacturer Name - Emcure Pharmaceuticals Ltd

WHAT IS OXALIPLATIN AND WHAT IT IS USED FOR:

Oxaliplatin is a platinum-based drug recommended in combination with the infusional 5­-fluorouracil /leucovorin, which is indicated for: 

  • adjuvant treatment of the stage-3 colon cancer in those patients who have undergone complete resection of the primary tumor. 
  • treatment of advanced colorectal cancer.
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Oxaliplatin Dosage

Oxaliplatin injection should be administered to you through your veins (blood vessels) under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. Precise management of the therapy and complications is possible only when the adequate diagnostic and treatment options or facilities are easily as well as promptly available.

Oxaliplatin side effects

Most common side effects include anemia, fatigue, neutropenia, thrombocytopenia, nausea, emesis, increase in transaminases and alkaline phosphatase, diarrhoea, stomatitis and peripheral sensory neuropathy. Other side effects, including serious adverse reactions, have been observed.

Warnings and Precautions
  • Some patients with this medicine may experience an allergic reaction to the platinum-containing medications. This is more often in women.
  • Patients should be monitored for the development of rash, urticaria, erythema, pruritus, bronchospasm, and hypotension.
  • Oxaliplatin has a little bit less ototoxicity and nephrotoxicity than carboplatin and cisplatin.
  • If you’re taking inj oxaliplatin, you must avoid cold temperatures and cold objects. Cover your skin if you go outside in cold temperatures. Cold drinks or use of ice cubes in drinks is not recommended. Putting ice or ice packs on your body should be avoided.
  • Patients must be advised to contact their healthcare provider if persistent vomiting, signs of dehydration, diarrhea, cough or breathing difficulties occur, or signs of allergic reaction appear.
  • Patients receiving oxaliplatin 100 mg plus 5-fluorouracil/leucovorin and requiring oral anticoagulants may need to be closely monitored.
  • Standard monitoring of the WBC country (white blood cell count) with differential, hemoglobin, platelet count, and blood chemistries (including ALT, AST, bilirubin and creatinine) is recommended prior to each OXA 100 cycle.
Supplied/Storage and handling

Care should be exercised in the handling of this drug. OXA injection should not be opened or crushed. Store permitted between 15-30°C (59-86°F).

Drug interaction of Oxaliplatin
  • Ventricular arrhythmias and QT interval prolongation can occur with Oxaliplatin. Avoid co-administration of Oxaliplatin with medicines with a known potential to prolong the QT interval.
  • Because the platinum-containing species are basically eliminated primarily through the kidney, the clearance of these products may be reduced by co-administration of potentially nephrotoxic compounds. Avoid the use of Oxaliplatin along with medicines known to cause nephrotoxicity.
  • INR and prolonged prothrombin time occasionally related with hemorrhage have been observed in patients who received Oxaliplatin along with fluorouracil/leucovorin while on anticoagulants. Increase the frequency of monitoring in patients who are receiving Oxaliplatin together with fluorouracil/leucovorin and oral anticoagulants.

Commonly asked questions:

This drug must be given by an injection into the vein.

Numbness, feeling tired, nausea, diarrhoea, and low blood cell counts are common adverse reactions.

This medication belongs to the platinum-based antineoplastic family of medications.

The active ingredient is Oxaliplatin, and the inactive ingredient is water for injection.

Yes, in 1976 Oxaliplatin was patented and in 1996 it was approved for medical use.

Fetal harm may occur when this drug is administered to the pregnant woman.

OXA 100 injection is believed to work by blocking the duplication of the DNA.

According to the experience, patients who took an overdose of Oxaliplatin have shown adverse reactions such as grade 4 thrombocytopenia, gastrointestinal disorders, grade 4 dehydration, dyspnea, wheezing, chest pain, respiratory failure, and severe dehydration, bradycardia, and death. If one takes an overdose, consult the doctor immediately and keep the patient under observation.

  • You can buy Oxaliplatin 100 mg, 50 mg from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at [email protected]. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician

Do not crush or open the injection.
Store the medicine at temperature 15-30°C (59-86°F).

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Oxaliplatin Injection is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.