Palbociclib

  • Brand Name - Palbace
  • Innovator Brand Name - Ibrance
  • API - Palbociclib
  • Packaging - 21 Capsules
  • Strength - 75 mg, 100 mg & 125 mg
  • Manufacturer Name - Pfizer Ltd.

WHAT IS PALBOCICLIB AND WHAT IT IS USED FOR:

Palbace is a kinase inhibitor indicated for the treatment of HR-Positive, HER2-Negative advanced as well as metastatic breast cancer in the combination with:

  • An aromatase inhibitor:

As an initial endocrine-based therapy in postmenopausal women.

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Palbociclib Dosage

Palbace should be taken orally at about the same time each day with food. Palbociclib capsules should be gulped wholly with water. You shouldn’t take opened, crushed,chewed, or broken capsules.

Palbociclib side effects

Most common adverse reactions include mouth sore, low red blood cells count, nosebleeds, dizziness, tiredness, weakness, hair thinning, diarrhea and nausea.

Serious side effects of palbociclib include fertility problems in males, bruising and shortness of breath.

Warnings and Precautions
  • Palbociclib 125 mg may cause fetal harm whenever administered to pregnant women.
  • Patients taking Palbace 125 mg should have their complete blood counts monitored at the beginning of each cycle also on day 15 of an initial couple of cycles and as clinically indicated.
  • Should be interrupt or permanently disclose the dose of Palbace 100 mg in the patients with worsening respiratory symptoms.
Supplied/Storage and handling

Care should be exercised in the handling of Palbociclib. PALBACE capsules should not be opened or crushed. Store permitted between 20-25°C (68-77°F).

Drug interaction of palbociclib
  • Co-administration of a strong CYP3A inhibitor increased the plasma exposure of palbociclib in healthy subjects by 87%. Avoid concomitant administration of strong CYP3A inhibitors (e.g., lopinavir/ritonavir, clarithromycin, itraconazole, indinavir, ketoconazole, nelfinavir, posaconazole, nefazodone, ritonavir, saquinavir, telaprevir, voriconazole, and telithromycin.
  • Avoid grapefruit or grapefruit juice while on palbociclib treatment. In case coadministration of palbociclib with a strong CYP3A inhibitor cannot be avoided, reduce the dosage of palbociclib.
  • Coadministration of a strong CYP3A inducer reduced the plasma exposure of palbociclib in healthy subjects by 85 percent. Avoid concomitant administration of strong CYP3A inducers (e.g., rifampin, phenytoin, carbamazepine, enzalutamide, and St John’s Wort).
  • The dosage of sensitive CYP3A4 substrates with narrow therapeutic indices may be required to be reduced when administered concurrently with palbociclib.

Commonly asked questions:

Palbociclib is a targeted therapy; it targets cyclin-dependent kinases.

Yes.

The active ingredient is Palbociclib, and the inactive ingredients are microcrystalline cellulose, colloidal silicon dioxide, crospovidone, magnesium stearate, succinic acid, HPMC 2910/hypromellose, titanium dioxide, triacetin, and FD&C Blue #2/Indigo Carmine Aluminum Lake.

Palbociclib is a kinase inhibitor drug that targets cyclin-dependent kinase.

  • Palbociclib 75 mg
  • Palbociclib 100 mg
  • Palbociclib 125 mg
  • You can buy Palbociclib from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • Although the palbociclib price may vary from pharmacy to pharmacy and of course brand to brand, so make sure that always choose a legitimate pharmacy(online or offline)
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician

Do not open or crush the capsules of medicine Palbociclib. Store the medicine at a temperature of 20-25°C (68-77°F).

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Palbociclib is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.