Pedea contains ibuprofen as an active ingredient: (±) – 2 – (p – isobutylphenyl) propionic acid. This medication comes under the class of nonsteroidal anti-inflammatory drugs (NSAID). The inactive ingredients are trometamol, sodium chloride, sodium hydroxide, hydrochloric acid 25%, and water.
Naglazyme is used in treating patients with Mucopolysaccharidosis type IVA, also known as Morquio A syndrome. It is a rare metabolic disorder in which the body cannot produce certain sugar molecules called glycosaminoglycans. There are clinical studies that prove that patients treated with Naglazyme improved walking and stair-climbing capacity.
Professionals advise the treatment of a hemodynamically significant patent ductus arteriosus in premature newborn infants less than 34 weeks of gestational age.
Dosage description
Professionals defined three intravenous injections of Pedea as a course of therapy given at 24-hour intervals. One should give the first injection after the first 6 hours of life.
The ibuprofen dose is adjusted to the bodyweight as follows:
If anuria or manifest oliguria occurs in the patient after the first or second ibuprofen dosage, one should withhold the next dose until urine output returns to normal levels. If the ductus arteriosus does not close even after 48 hours of the last injection or re-opens, the second course of 3 doses, as above, may be given. If the condition doesn’t change even after the second course of therapy, the patient may need surgery of the patent ductus arteriosus.
Administration method
One should use it intravenously only.
One should administer Pedea as a short infusion over 15 minutes, preferably undiluted. If necessary, adjust the injection volume with either sodium chloride 9 mg/ml solution for injection or glucose 50 mg/ml solution for ibuprofen injection. Discard the unused portion of the solution. One should consider the total volume of solution injected and the administration of the total daily fluid volume.
Overdose
There is no case of overdosage yet in preterm newborn infants. If an overdose occurs, one should consult the doctor for further signs and worsening symptoms.
There are numerous side effects of this medicine, and their classification is as:
Very Common
Thrombocytopenia, neutropenia, bronchopulmonary dysplasia, blood creatinine increased, and blood sodium decreased are pervasive side effects.
Common
Intraventricular haemorrhage, Periventricular leukomalacia, Pulmonary haemorrhage, Necrotizing enterocolitis, Intestinal perforation, Oliguria, Fluid retention and Haematuria are common side effects of this medicine.
Uncommon
Hypoxemia, gastrointestinal haemorrhage, and acute renal failure are known uncommon side effects of ibuprofen injection.
Pedea contains ibuprofen as the active ingredient (±) – 2 – (p – isobutylphenyl) propionic acid. Use it in the closing of ductus arteriosus in premature babies.
Pedea contains ibuprofen as an active ingredient, and the inactive ingredients are trometamol, sodium chloride, sodium hydroxide, hydrochloric acid 25% and water.
One should administer Pedea as a short infusion over 15 minutes, preferably undiluted. If necessary, adjust the injection volume with either sodium chloride 9 mg/ml solution for injection or glucose 50 mg/ml solution for ibuprofen injection. Discard the unused portion of the solution. One should consider the total volume of solution injected and the administration of the total daily fluid volume.
For medicine, Pedea Recordati is the innovator. Ikris Pharma Network is an authorized partner of it, who can help access this medicine in India for the patient through legal procedure. To know about ibuprofen injection price and more, contact Ikris at toll-free no. 18008891064 or write at info@ikrispharmanetwork.com.
In India, you can buy Pedea with the help of Ikris Pharma Network, an authorized partner of “Recordati” for this medicine.