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Piperacillin/Tazobactam

  • Packaging - Powder for Solution for Infusion
  • Strength - 4g/0.5g
  • Generic Brand Available - pipramed
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What is Piperacillin Tazobactam, and what it is used for?

The piperacillin and tazobactam is a combination penicillin-class antibacterial and β-lactamase inhibitor used for treatment of:

1. Intra-abdominal infections

2. Skin and skin structure infections

3. Female pelvic infections

4. Community-acquired pneumonia

5. Nosocomial pneumonia

Piperacillin/Tazobactam dosage

Piperacillin/Tazobactam should be administered by intravenous infusion over 30 minutes. The usual daily dose of piperacillin tazobactam for adults is 3.375 g every 6-hours totaling 13.5 g (12.0 g piperacillin/1.5 g tazobactam).

Nosocomial Pneumonia: The initial presumptive therapy of patients with nosocomial pneumonia should start with dosage piperacillin tazobactam 4.5 g every six hours plus an aminoglycoside, totaling 18.0 g (16.0 g piperacillin/2.0 g tazobactam).
For children with peritonitis and/or appendicitis the recommended piperacillin and tazobactam injection ip dosage is 100 mg piperacillin/12.5 mg tazobactam per kg of body weight, every 8-hours in pediatric patients aged 9 months and older. For pediatric patients aged 2 to 9 months, the standard dosage is 80 mg piperacillin/10 mg tazobactam per kg of body weight, every 8-hours.

Side Effects

The most commonly reported Piperacillin Tazobactam side effects include: diarrhea, constipation, headache, nausea and insomnia.

Warnings and Precautions
  • The use of piperacillin tazobactam 4.5 g is restricted in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or β-lactamase inhibitors.
  • Prior to initiating therapy with piperacillin and tazobactam injection ip 4.5 gm, careful inquiry should be made concerning any kind of previous hypersensitivity reactions.
  • Dosage in patients with renal impairment (≤40 mL/min of CRCL) and dialysis patients should be decreased, on behalf of the degree of actual renal function impairment.
  • In case patients develop a skin rash they should be evaluated closely and piperacillin tazobactam discontinued if lesions progress.
  • Periodic assessment of hematopoietic function needs to be performed, especially with prolonged therapy, ie, ≥ 21 days.
  • As with other existing penicillins, patients may have neuromuscular excitability or convulsions if greater than prescribed doses of piperacillin tazobactam injection are given intravenously (mainly in the presence of renal failure).
  • The combined administration of vancomycin and piperacillin/tazobactam may be associated with an increased incidence of acute kidney injury.
How Supplied/Storage and Handling:

The piperacillin tazobactam injection vials should be stored at controlled room temperature (20°C to 25°C [68°F to 77°F]) prior to reconstitution.

Commonly asked questions:

Piperacillin Tazobactam is a combination drug containing the antibiotic piperacillin and the β-lactamase inhibitor tazobactam. It has activity against several Gram +Ve and Gram -Ve bacteria including Pseudomonas aeruginosa. It aimed to treat pelvic inflammatory disease, cellulitis, intra-abdominal infection, pneumonia, and sepsis.

The piperacillin tazobactam iv medicinal product is supplied as 4 g/0.5 g Powder for Solution for Infusion.

The Piperacillin Tazobactam comes as an injection for intravenous infusion. 

Piperacillin Tazobactam specifically is a type of antibacterial and β-lactamase inhibitor drug. 

You can buy piperacillin and tazobactam injection from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial Toll-Free number: 18008891064. We will reply ASAP with the details of the piperacillin tazobactam price as well as procurement procedure.

Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

Disclaimer

All Trademarks and Brands that appear on website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. We are NOT ONLINE store and We do not sell Narcotics and Sedatives. Piperacillin Tazobactam combination is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller, and Pharmacies.