Register Now: IKRIS Breast Cancer Awareness Run 2022

Polymyxin B

  • Generic Brand Name - Polykris
  • API - Polymyxin-B
  • Packaging - Single vial
  • Strength - 500000 IU

What is Polymyxin B, and what it is used for:

Polymyxin-B Injection is used to treat patients with the following infections when caused by susceptible strains of the designated aerobic gram-negative bacteria:

  • Urinary tract infections: Caused by the Pseudomonas aeruginosa and Escherichia coli. 
  • Bloodstream infections: Caused by the Pseudomonas aeruginosa, Enterobacter (formerly known as Aerobacter) aerogenes and Klebsiella pneumonia. 
  • Meningeal infections: Caused by the Pseudomonas aeruginosa. 
  • Corneal and subconjunctival eye infections: Caused by Pseudomonas aeruginosa.

The recommended dose of Polymyxin B Injection may be administered intravenously, intramuscularly or intrathecally only to hospitalized patients under the constant supervision by a healthcare professional. The polymyxin b dosage should not exceed 2.5 mg/kg/day or 200 mg/day.

side effects

The most commonly reported side effects of polymyxin B include neurotoxicity, pain at the injection site, electrolyte imbalance, and urticaria.

Warnings And Precautions
  • Therapy with polymyxin B USP 500000 IU shouldn’t be used in individuals with a prior history of hypersensitivity reactions to it.
  • The polymyxin B sulfate Injection, if prescribed for the administration of intravenous, intramuscular, or intrathecal, should be used only in hospitalized patients under precise monitoring for kidney function and neurological signs/symptoms.
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of Inj polymyxin B dose and other antibacterial drugs, it should be used only to treat/prevent infections that are proven to be caused by susceptible bacteria.
  • The Inj polymyxin B dose should not be used in patients with myasthenia gravis.
  • Polymyxin-B Injection is nephrotoxic; therefore, the renal function should be evaluated before and regularly while on treatment.
  • Polymyxin-B sulphate injection should be used with extreme caution in patients with porphyria.
  • The polymyxin B uses are restricted during pregnancy unless the expected benefit to the mother outweighs any potential risk to the fetus.
How Supplied/Storage and Handling:

Care is exercised in the handling of Polymyxin B. It should not be open or broken. Polymyxin B Injection should be stored at temperature 20°C to 25°C (68°F to 77°F)

Drug Interaction
  • The concurrent use of other nephrotoxic/neurotoxic drugs, particularly bacitracin, streptomycin, kanamycin, tobramycin, cephaloridine, amikacin, cephalothin, polymyxin E (colistin), neomycin, vancomycin, and gentamicin, should be avoided.
  • Because of the effect of polymyxin antibiotic drug on the release of acetylcholine, depolarizing muscle relaxant succinylcholine and other neurotoxic drugs must not be used concurrently with polymyxin sulphate.
  • The concurrent use of polymyxin b sulphate with potent diuretics such as ethacrynic acid or furosemide should be avoided, since diuretics can enhance polymyxin B sulphate toxicity by altering the antibiotic concentration in serum and tissues.

Commonly asked questions:

Polymyxin-B is an antibiotic. It acts by breaking down the cytoplasmic membrane, which results in the death of bacterial cells.

The recommended dose of polymyxin b injection should be administered by injection into a vein, muscle, or intrathecally. 

You can buy Polymyxin-B directly from Ikris Pharma, make sure you have a valid prescription while buying.

Patients can simply fill the order form or can send mail at Patients can also send WhatsApp messages to +91 8130290915 or can dial Toll-Free number: 18008891064. We will reply ASAP with the details of polymyxin b price and buying procedure.

Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

Yes, Polykris is Polymyxin-B generic brand, It is manufactured by Ikris Pharma. For polymyxin b injection price in India Call/Whatsapp us on +91 8130290915, you can also dial our TOLL-FREE 18008891064 or mail us at


All Trademarks and Brands that appear on the website belong to their respective owners, and Ikris Pharma Network does not claim them. We only provide details. Polymyxin-B is Ikris Pharma own-label brand and we requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, Reseller, and Pharmacies.