Regorafenib

  • Brand Name - Nublexa
  • Innovator Brand Name - Stivarga
  • API - Regorafenib
  • Packaging - 28 Tablets
  • Strength - 40 mg
  • Manufacturer Name - Bayer

WHAT IS REGORAFENIB AND WHAT IT IS USED FOR:

Regorafenib is a multi-kinase inhibitor, indicated for the treatment of:

  • Metastatic Colorectal Cancer
  • Advanced Hepatocellular Carcinoma
  • Also, Advanced Gastoinstenstial Stromal Tumors

 

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Regorafenib Dosage

Nublexa should be taken orally at the same time each day, after taking a low-fat meal. Nublexa 40 mg tablets should be gulped wholly with water. Tablets should not be opened, broken, chewed or split.

Regorafenib side effects

Most common adverse reactions may include Weakness, Fatigue, Loss of Appetite, desquamation on palm, mouth sores, weight loss, change in voice quality.

Also, some serious side effects of Regorafenib may occur include severe bleeding, peeling of the skin and high blood pressure.

Warnings and Precautions
  • Regorafenib 40 mg is not recommended for females during pregnancy.
  • Nublexa tablets may be responsible for Hemorrhage and Hypersensitivity.
  • Nublexa may lead the patient towards Dermatologic Toxicity, be very watchful while taking and consult with your health care provider.
  • Do not go with Immunization as well as vaccination while using Regorafenib until you get the consent of your health care provider.
Supplied/Storage and handling

Care should be implemented in the proper handling of Regorafenib. Nublexa (Regorafenib) tablets should not be opened or crushed unnecessarily.

The store permitted for Nublexa between the range from  15-30 C (59-86 F).

Drug interaction of Regorafenib
  • Co-administration of a strong CYP3A4 inducer (rifampin) with a single dose of Regorafenib 160 mg decreased the mean exposure of regorafenib, increased the mean exposure of the active metabolite M-5, and resulted in no change in the mean exposure of the active metabolite M-2. Avoid the concomitant administration of strong
  • CYP3A4 inducers (e.g. carbamazepine, rifampin, phenytoin, phenobarbital, and St. John’s Wort).
    Co-administration of a strong CYP3A4 inhibitor (ketoconazole) with a single dose of Regorafenib 160 mg increased the mean exposure of regorafenib and reduced the mean exposure of the active metabolites M-2 and M-5. Avoid concomitant administration of strong inhibitors of CYP3A4 activity (e.g. grapefruit juice, clarithromycin, itraconazole, posaconazole, telithromycin, ketoconazole and voriconazole).

Commonly asked questions:

Colorectal cancer is cancer in the colon or rectum (parts of the large intestine).

Regorafenib prescription anticancer medicine for patients who have received previous treatment with certain chemotherapy medicines.

Yes.

The active ingredient in the medicine is Regorafenib, and the inactive ingredients are cellulose microcrystalline, croscarmellose sodium, magnesium stearate, povidone, and colloidal silicon dioxide.

People who should avoid the administration of medicine Regorafenib:
Have liver problems
Have bleeding problems
Have high blood pressure
Have heart problems
Have had recent surgery
Pregnant or planning to become pregnant males and females
Allergic to ingredients of the medicine

  • Regorafenib price for generic one is low as compare to innovator brand, you can buy Regorafenib from any authorized whole seller after getting prescription from a qualified doctor. It is always better to check the credential of the whole seller/supplier/exporter before buying the product.
  • The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at [email protected]. Patient can also send WhatsApp message to +91 8130290915. We will reply ASAP with the details of Pricing and procedure.
Note:- The order will be confirmed only after the receipt of Valid prescription of Clinician.

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Regorafenib 40 mg is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, reseller and Pharmacies.