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Sunitinib

  • Generic Brand Name - Suninat
  • Manufacturer Name - Natco Pharma Ltd.
  • Innovator Brand Name - Sutent
  • API - Sunitinib Malate
  • Packaging - 28 Capsule
  • Strength - 50 mg

What is Sunitinib and what it is used for:

SUNITINIB is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor drug indicated for the treatment of: 

  • Gastrointestinal Stromal Tumor (GIST) following disease progression or intolerance to imatinib mesylate.
  • Advanced Renal Cell Carcinoma (RCC).
  • Advanced Pancreatic Neuroendocrine Tumors (pNET). 
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Sunitinib Dosage
  • Take suninat exactly the way your doctor tells you. It should be taken 1 time each day with or without food.
  • If you take suninat for GIST or RCC, you will usually take your capsules for 4 weeks (28 days) and then stop for 2 weeks (14 days). This is 1 cycle of treatment. You will be prescribed to repeat this treatment cycle for as long as your doctor tells you to.
  • If you take suninat for pNET, take it 1 time every day until your doctor tells you to stop.
  • If you forget a suninat dose by less than 12 hours, take the forgotten dose as soon as you can. If you forget a sunitinib dose by more than 12 hours, just take your next dose at about your regular time. Avoid making up the missed dose.
    Contact your healthcare practitioner right away, if you take an excess dose of suninat.
Sunitinib side effects

Most common adverse reactions include, loss of appetite, tiredness, weakness, diarrhea, pain, swelling or sores inside of your mouth, nausea, indigestion, vomiting, stomach-area (abdominal) pain, blisters or rash on the palms of your, hands and soles of your feet, low platelet counts, high blood pressure, and taste changes.

Warnings And Precautions
  • Your healthcare practitioner will do blood tests prior to each cycle of the treatment in order to check you for sunitinib side effects.
  • In patients with diabetes, blood glucose levels should be checked at the regular basis to assess if anti diabetic drug dosage needs to be adjusted in order to minimise the risk of hypoglycaemia.
  • The therapy of sunitinib needs to be discontinued in patients with the necrotising fasciitis and appropriate treatment is promptly initiated.
  • Patients need to be instructed that depigmentation of the hair/skin may also appear while on treatment.
  • Sunitinib should be avoided during pregnancy. Women of childbearing potential must avoid conceiving a baby while on this drug.
  • Women on this medication should not breastfeed.
  • Avoid drinking grapefruit juice or eat grapefruit during your treatment with this drug. They may cause you to have excess drugs in your body.
Storage and Handling

Care should be exercised in the handling of SUNITINIB. SUNITINIB Capsules should not be opened or crushed. Store the capsules at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).

Drug interaction of sunitinib
  • Consider dose reduction of sunitinib when administered along with strong CYP3A4 inhibitors.
  • Consider dose increase of sunitinib when administered along with CYP3A4 inducers.

Commonly asked questions:

The active ingredient in the medicine is Sunitinib, and the inactive ingredients are mannitol, croscarmellose sodium, povidone (K-25), and magnesium stearate.

FDA approved this medicine in 2006 for treating gastrointestinal stromal tumors, advanced renal cell carcinoma, pancreatic neuroendocrine tumors, etc.

The medication sunitinib 25 mg belongs to the group of drugs named antineoplastics.

People who should avoid the administration of this medicine are following:

  • Patients with heart-related problems.
  • Patients with high blood pressure.
  • Patients with thyroid.
  • Patients with a history of low blood sugar or diabetes.
  • Patients with kidney function problems.
  • Patients with liver problems.
  • Patients with any bleeding problem.
  • Patients who have had pain in the mouth, teeth, or jaw, swelling or sores inside the mouth, numbness or a feeling of heaviness in the jaw, or loosening of a tooth.
  • Pregnant or planning to become pregnant females and males.

Fatigue, nausea, diarrhea, anorexia, a yellow skin discoloration, hypertension, hand-foot skin reaction, and stomatitis are few common side effects of sunitinib.

Swallow the sutent 50 mg capsules whole. It is not recommended to split, chew, or crush and open them. You need to take your capsules as exactly prescribed by your doctor.

In order to block a particular enzyme from acting, sunitinib 50 mg can resist the growth of cancerous cells. As a targeted therapy it works in order to block the two processes that allow cancerous cells to grow. Foremost, it interferes with a kind of protein that helps in promoting the cell division.

You can buy sunitinib 50 mg drug from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product.

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patients can also send a WhatsApp message to +91 8130290915. We will reply ASAP with the details of Sutent 50 mg price and procedure.

Note:- The order will be confirmed only after the receipt of the Valid prescription of Clinician.

Disclaimer

All Trademark and Brand that appear on the website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. Sunitinib Malate Capsule is a pharmaceutical drug that legally requires a medical prescription to be dispensed.
Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Corporate Sourcing, Reseller and Pharmacies.