Thiotepa dosage should be taken intravenously under an experienced healthcare provider.
It is an alkylating agent indicated for the treatment of:
Thiotepa dosage should be taken intravenously under an experienced healthcare provider.
The common side effects of thiotepa include vomiting, abdominal pain, nausea, anorexia, fatigue, rash, weakness, urticaria, laryngeal edema, anaphylactic shock, asthma, wheezing, contact dermatitis, pain at the injection site, vision dizziness, blurred vision, headache, dysuria, urinary retention, chemical cystitis, amenorrhea, conjunctivitis and interference with the spermatogenesis.
Care should be exercised in the handling of THIOTEPA. Vials should not be opened or crushed. Store permitted between 2°C to 8°C (36° to 46°F). Do not freeze it.
Thiotepa is a cytotoxic agent. The radiomimetic action of thiotepa is believed to occur through the release of ethyleneimine radicals which, like irradiation, disrupt the bonds of DNA.
Thiotepa is basically an alkylating agent.
The active ingredient in the medicine is Thiotepa and the inactive ingredient is water for injection.
In an event of overdose, patients may experience most important adverse reactions: myeloablation and pancytopenia.
Hypersensitivity to the active substance and Concomitant use with live or attenuated vaccines.
It is also used in the palliation of many neoplastic diseases. The best outcomes are found in the treatment of adenocarcinoma of the ovary and breast, papillary thyroid cancer and bladder cancer. It is recommended to control the intracavitary effusions caused by the serosal neoplastic deposits.
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Store the medicine Thiotepa at temperature 2°C to 8°C (36° to 46°F).
Do not freeze the medicine.
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