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Tigecycline

  • API - Tigecycline
  • Packaging - Single-dose 5 mL vial
  • Strength - 50 mg
  • Available Brand - Generic brand of Tigecycline

What is Tigecycline, and what it is used for:

Tigecycline is a tetracycline-class antibacterial used in patients aged 18 years and older for: 

  • Complicated skin and skin structure infections 
  • Complicated intra-abdominal infections 
  • Community-acquired bacterial pneumonia
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Dosage

The recommended dosage regimen for tigecycline injection is an initial dose of 100 mg, followed by 50 mg every 12 hours. The intravenous infusions of tigecycline should be administered over about 30-60 minutes every 12 hours. The recommended duration of therapy with tigecycline for complicated skin and skin structure infections or for complicated intra-abdominal infections is 5-14 days. The recommended duration of therapy with tigecycline for the community-acquired bacterial pneumonia is 7-14 days. Duration of therapy must be guided through the severity & site of the infection and the patient’s clinical as well as bacteriological progress.

Side effects

Commonly reported side effects are incidence >5% in patients treated with tigecycline 50 mg injection include:

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Headache
  • Increased SGPT
Warnings and Precautions
  • Use of tigecycline 50 mg injection is contraindicated in patients with known hypersensitivity to this drug.
  • Patients with tigecycline and who established abnormal liver function tests should be assessed for evidence of worsening hepatic function and evaluated for the risk or benefit of continuing tigecycline therapy.
  • Administration tigecycline 50 mg injection may cause fetal harm to pregnant women. In case the patient becomes pregnant while on therapy, the patient must be apprised of the potential risk to the fetus.
  • The use of tigecycline during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may be responsible for causing permanent discoloration of the teeth (yellow-gray-brown).
  • Caution should be imposed if using tigecycline 50 mg monotherapy in recipients with complicated intra abdominal infections secondary to the clinically apparent intestinal perforation.
  • As with certain other antibacterial agents, tigecycline injection uses may cause excess growth of non-susceptible organisms, including fungi. Patients must be precisely evaluated while on therapy. In case superinfection occurs, apt measures must be considered.
How Supplied/Storage and Handling:

Prior to reconstitution, Tigecycline should be stored at 20°C to 25°C (68°F to 77°F). The excursions permitted 15°C-30°C (59°F-86°F). Following the reconstitution, it could be stored at room temperature for up to 1-day/24-hours (up to six hours in the vial and the rest time in the intravenous bag). Alternatively, Tigecycline is mixed with 0.9% Sodium Cl Injection, USP or 5% Dextrose Injection, USP can be stored in refrigerator at 2°C to 8°C (36°F to 46°F) for up to 48 hours after immediate transfer of the reconstituted solution into the intravenous bag. The reconstituted solution must be transferred and further diluted for intravenous infusion.

Drug interaction of Tigecycline
  • Prothrombin time or other suitable anticoagulation test should be monitored in case tigecycline is administered along with warfarin.
  • Administration of antibacterial drugs along with oral contraceptives may render oral contraceptives less effective.

Commonly asked questions:

Tigecycline (Brand name Tygacil), specifically is a tetracycline antibiotic medicine prescribed for a number of bacterial infections.

Tigecycline should be administered only by intravenous infusion over 30 to 60 minutes. It should be preferably administered over a 60 minute length of infusion in paediatric patients.

You can buy Tigecycline from any authorized whole-seller after getting a prescription from a qualified doctor. It is always better to check the credential of the whole-seller/supplier/exporter before buying the product.

The buyer should check the existing law in their home country before importing the product. 

Patients can simply fill the order form or can send mail at info@ikrispharmanetwork.com. Patients can also send WhatsApp messages to +91 8130290915 or can dial Toll-Free number: 18008891064. We will reply ASAP with the details of tigecycline injection price and procedure.

Note:- The order will be confirmed only after the receipt of the Valid prescription of the Clinician.

 

Disclaimer

All Trademark and Brand that appear on website belong to their respective owners and Ikris Pharma Network does not lay and claim on them we only provide Information. We are NOT ONLINE store and We do not sell Narcotics and Sedatives. Tigecycline is a pharmaceutical drug that legally requires a medical prescription to be dispensed.

Following Information meant for Wholesalers, Suppliers, Exporters, Doctors, Comparator Supplies, Hospitals, Generic, Brand, Cooperate Sourcing, reseller and Pharmacies.